Resources for review authors

Resources for teaching and learning about applying the results of systematic reviews

  • Details on how to apply results of systematic reviews can be found in chapters 11 and 12 of The Cohrane Handbook for Systematic Reviews.
  • Online learning modules designed to help guidelines developers and systematic reviews authors learn how to use GRADE approach and moving from evidence to making recommendations.
  • Review authors, clinicians and policy-making persons may also consider the following 6-part BMJ series:
  1. Rating quality of evidence and strength of recommendations GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.
    BMJ 2008;336:924-926
  2. Rating  quality of evidence and strength of recommendations: What is "quality of evidence" and why is it important to clinicians? BMJ. 2008 May 3;336(7651):995-8 
  3. Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ 2008 May 17;336(7653):1106-10
  4. Rating quality of evidence and strength of recommendations: Incorporating considerations of resources use into grading recommendations.
    BMJ. 2008 May 24;336(7654):1170-3
  5. Rating quality of evidence and strength of recommendations: Going from evidence to recommendations.
    BMJ 2008 May 10;336(7652):1049-51
  6. Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive.  BMJ. 2008 Jul 31;337:a744 
  • A complete guide for systematic review and health technology assessment authors, guideline panelists and methodologists on how to apply the GRADE methodology framework can be found in the JCE series.

GRADE guidelines: A new series of articles in the Journal of Clinical Epidemiology.
J Clin Epidemiol. 2010 Dec 27

  1. GRADE guidelines 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011 Jan 3
  2. GRADE guidelines 2. Framing the question and deciding on important outcomes.
    J Clin Epidemiol. 2011 Jan 3
  3. GRADE guidelines 3: rating the quality of evidence - introduction.
    J Clin Epidemiol. 2011 Jan 6
  4. GRADE guidelines 4: rating the quality of evidence - risk of bias.
    J Clin Epidemiol. 2011 Jan 20
  5. GRADE guidelines 5: rating the quality of evidence - publication bias.
    J Clin Epidemiol. 2011 Aug 1
  6. GRADE guidelines 6. Rating the quality of evidence - imprecision.
    J Clin Epidemiol. 2011 Aug 12
  7. GRADE guidelines: 7. Rating the quality of evidence - inconsistency.
    J Clin Epidemiol. 2011 Aug 2
  8. GRADE guidelines: 8. Rating the quality of evidence - indirectness.
    J Clin Epidemiol. 2011 Aug 1
  9. GRADE guidelines: 9. Rating up the quality of evidence.
    J Clin Epidemiol. 2011 Aug 1