The Cochrane Handbook for Systematic Reviews of Interventions includes guidance on incorporating adverse effects in systematic reviews. A discussion paper on the methods used has also been published in BMC Medical Research Methodology.
Cochrane hosts a dedicated Cochrane Training website, containing online training modules on different aspects of conducting a Cochrane systematic review.
Cochrane also hosts Cochrane Learning Live which contains webinars on adverse effects such as Adverse effects 1: How to overcome the challenge of reviewing adverse effects and Adverse effects 2: Searching for adverse effects
To adjust for outcome reporting bias in trials see the ORBIT methods platform for researchers that can easily be applied by non-methodologists
For further information and advice please join our discussion list at http://lists.cochrane.org/mailman/listinfo/aemg or contact a member of our specialist advisory panel.