Cochrane News

Cochrane examines the evidence base for the effectiveness and implementation of Hospital at Home programmes

7 months 1 week ago

A new Cochrane Library Editorial has been released following the publication of two Cochrane systematic reviews on Hospital at Home (HAH) programmes, urging a shift in the trajectory of HaH research. 

Hospital at Home provides hospital-level care at home, for people who would otherwise be inpatients in hospital. One type of Hospital at Home is to avoid admission to hospital. This is called Admission Avoidance Hospital at Home. These services replace an admission to hospital, for people whose condition would normally need treatment in a hospital bed, for example for a flare-up of a lung condition. Instead, a doctor can refer a patient they assess as being suitable to receive treatment for an illness in their own home (or the place where they usually live, including in residential care), for a limited time. Another type is called Early Discharge Hospital at Home. These services shorten the length of time people need to stay in hospital after being admitted as an inpatient, for example following surgery or treatment for an illness or condition. The care patients would usually receive from healthcare professionals in a hospital bed is instead provided in their home, and is not expected to compromise the quality of care.

This first Cochrane review examined if providing health care in an admission avoidance hospital at home setting improves patient health outcomes and reduces health service costs.

Edgar K, Iliffe S, Doll HA, Clarke MJ, Gonçalves-Bradley DC, Wong E, Shepperd S. Admission avoidance hospital at home. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: CD007491. DOI: 10.1002/14651858.CD007491.pub3.


The second Cochrane review is a qualitative evidence synthesis on what is important when introducing, running, and receiving care from Hospital at Home services. The authors wanted to explore a range of experiences of, and views on, Admission Avoidance and Early Discharge services. Topics covered things that managers want to know when planning to set up a Hospital at Home service, healthcare professionals’ views on working in a Hospital at Home service, what matters to patients who receive this type of care, or how family and caregivers experience Hospital at Home services for those they care for.

Wallis JA, Shepperd S, Makela P, Han JX, Tripp EM, Gearon E, Disher G, Buchbinder R, O'Connor D. Factors influencing the implementation of early discharge hospital at home and admission avoidance hospital at home: a qualitative evidence synthesis. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: CD014765. DOI: 10.1002/14651858.CD014765.pub2. 

These two updated Cochrane reviews demonstrate HaH's clinical and cost-effectiveness but also show the lack of effective scale-up strategies. An accompanying Cochrane Library editorial strongly suggests that the future direction of HaH research must move beyond repeating clinical and cost-effectiveness studies comparing HaH to usual care and instead focus on identifying and testing strategies to increase adoption and sustainability across different healthcare systems. 

The authors summarized the Cochrane Library Editorial by saying:

This editorial recognises the conclusive evidence that Hospital at Home (HaH) programmes are comparable to traditional hospital care, and encourages the  shift in the discourse from “does HaH work?” to “how to we scale up HaH successfully?”. 

Key challenges that needs to be addressed are: patient and  caregiver engagement, policy development, and sustainability to integrate HaH as a core component of acute care strtagies.

Lai YF, Ko SQ. Time to shift the research agenda for Hospital at Home from effectiveness to implementation. Cochrane Database of Systematic Reviews 2024, Issue 3. Art. No.: ED000165. DOI: 10.1002/14651858.ED000165.

Tuesday, March 5, 2024
Muriah Umoquit

Cochrane seeks Product Manager (permanent, UK remote)

7 months 1 week ago

Specifications: Permanent – Full Time
Salary:  £40,000 per Annum  
Location: UK (Remote) with occasional travel to London Office
Closing date: 7 March 2024

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

You will manage the product roadmap and product lifecycle for commercial products, primarily focusing on the development of premium product offerings which leverage Cochrane evidence and content.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

  • An opportunity to truly impact health globally.  
  • A flexible work environment  
  • A comprehensive onboarding experiences.
  • An environment where people feel welcome, heard, and included, regardless of their differences.

Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  • For further information on the role and how to apply, please click here
  • The deadline to receive your application is 07 March, 2024.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
  • Read our Recruitment Privacy Statement
Thursday, February 22, 2024 Category: Jobs
Lydia Parsonson

Cochrane seeks Governance Officer (permanent, remote UK)

7 months 2 weeks ago

Specifications: Permanent – Full Time
Salary:  £31,000 per Annum
Location: UK (Remote with occasional travel to the London office)
Directorate: CEOO
Closing date:  05 March 2024

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Governance Officer works at the most senior level in the organisation, ensuring the smooth running of Cochrane’s governance function and the systems and processes that support it.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values:

Collaboration: Underpins everything we do, locally and globally.

Relevant: The right evidence at the right time in the right format.

Integrity: Independent and transparent.

Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

  • An opportunity to truly impact health globally.
  • A flexible work environment
  • A comprehensive onboarding experiences.
  • An environment where people feel welcome, heard, and included, regardless of their differences.

Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  • For further information on the role and how to apply
  • The deadline to receive your application is 5th March, 2024.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples.
  • Read our Recruitment Privacy Statement
Tuesday, February 20, 2024 Category: Jobs
Lydia Parsonson

Cochrane Sweden wrongly suspended from social media platform X

7 months 2 weeks ago

Last week, a report co-authored by Cochrane Sweden revealed that the results of hundreds of Nordic clinical trials remain unpublished. The team shared the report on the social media platform X, formerly known as Twitter. Two days later, their account was suspended from the platform following reports from unknown users. The team are appealing the decision but have had no response so far.

Since 2019, Cochrane Sweden have been involved in improving trial transparency, publishing reports and organizing international webinars. The latest report found that 475 clinical trials involving 83,903 patients completed during 2016-19 in Denmark, Iceland, Finland, Norway and Sweden have never made their results public in any form.



“We shared the report on Nordic trial transparency on Tuesday 6 February, and by Thursday our Cochrane Sweden X account was suspended unexpectedly,” says Matteo Bruschettini, Director of Cochrane Sweden and co-author of the report. “We have initiated an appeal against the suspension, which is apparently for ‘pretending to be another entity in a misleading or deceptive manner’. We suspect that we were reported maliciously in response to our latest report, which is extremely unfortunate. We are currently considering whether to dismiss X and focus on other social media channels.”


X’s rules on ‘platform integrity and authenticity’ state that accounts will be suspended if they are ‘engaged in impersonation or are using a deceptive identity’. This is clearly not the case for Cochrane Sweden’s X account, which has always been run by Cochrane Sweden.

This is not the first time that Cochrane-affiliated social media channels have been erroneously censored by social media platforms. During the COVID-19 pandemic, Cochrane social media posts sharing evidence that ivermectin and hydroxychloroquine were ineffective treatments were removed from various social media platforms and wrongly tagged as ‘misinformation’.



“It’s disturbing to see that social media rules aimed at preventing misinformation are being used to do the exact opposite,” says Catherine Spencer, Chief Executive of the Cochrane Collaboration. “Social media platforms must do more to protect trusted sources from vexatious or malicious reports, and act swiftly to correct things when they make a mistake. Cochrane Sweden’s important work to promote research integrity has been undermined by rules ostensibly aimed at safeguarding integrity and authenticity. We stand behind Cochrane Sweden and urge X to restore their account as soon as possible.”

Friday, February 16, 2024
Harry Dayantis

Cochrane launches new Interactive Learning module on qualitative evidence synthesis

7 months 2 weeks ago

Cochrane is delighted to announce the launch of the twelfth module within the Cochrane Interactive Learning course, on qualitative evidence synthesis (QES). 

This introductory module teaches participants how to systematically combine and analyze evidence from individual qualitative studies. The module, designed to be completed in about 90 minutes, aims to provide participants with a solid foundation in framing a QES question, scoping a topic, assessing available evidence, synthesizing data, and proficiently presenting findings in a comprehensive report.

Professor Jane Noyes, one of the module's authors, says "This module aims to provide learners with a basic overview of designing and conducting a QES. We prioritized the key methods and stages in the design and conduct of a qualitative evidence synthesis."

QES has emerged as a crucial approach for informing guideline development and addressing implementation considerations in diverse country settings and complex health systems.

"We're dedicated to meeting the needs of our end-users by diversifying the evidence we offer in the Cochrane Library. Embracing qualitative evidence synthesis strengthens our capacity to fulfill these needs. I'm thankful for the dedication of the Methods QES Group, whose efforts-from the groundbreaking Cochrane Interactive Learning to the influential Cochrane-Campbell Handbook-advance the dissemination of qualitative evidence synthesis, fostering a future where every voice is valued," Karla Soares-Weiser, Editor in Chief of the Cochrane Library, says.

Developed by the Cochrane Qualitative and Implementation Methods Group in collaboration with the Learning Team in Cochrane's Development Directorate, the twelfth module reflects dedication to delivering high-quality, engaging, and innovative distance learning experiences.

The module includes links to relevant chapters from the Cochrane-Campbell Handbook for Qualitative Evidence Synthesis, allowing learners to access more detailed methods guidance for those seeking in-depth information.

Andrew Booth, who also authored the module, shares his excitement: "Having spent over a decade delivering face-to-face training events on qualitative evidence synthesis, it was really exciting to be steered towards explaining the same concepts and techniques for an international online community."

Notably, certain Cochrane contributors and residents of HINARI countries may access the new module and the entire Cochrane Interactive Learning course free of charge. Additionally, subscription options are available for both individuals and institutions interested in accessing this valuable resource. For further details and to access the new module, please visit the Cochrane Interactive Learning page.

May Silveira Bianchim, a Cochrane Qualitative and Implementation Methods Group (QIMG) intern, underscores the value of the introductory module in her professional development: "As a Cochrane QMIG intern, the introductory module is an invaluable resource for learning the basic steps of qualitative evidence synthesis, providing insights that are instrumental in applying this knowledge to practice. This experience has been meaningful to my ongoing professional development."

Friday, February 16, 2024
Christine Maema

Hundreds of Nordic clinical trials remain unpublished

7 months 3 weeks ago

A new report jointly published by the AllTrials campaign, Cochrane Denmark, Cochrane Norway, Cochrane Sweden, the Dam Foundation, Melanomföreningen, and TranspariMED found that 475 clinical trials involving 83,903 patients completed during 2016-19 in Denmark, Iceland, Finland, Norway and Sweden have never made their results public in any form. This accounted for 22% of all clinical trial results across the five countries.

In cases where clinical trial results were made public, there was often a delay in publication. The report found that only 27% of all trials results were made public, in either registries or in journals, within 12 months. Within two years of study completion, only around half of the results were available to the public.

Not only is this lack of transparency in clinical trials a waste of increasingly scarce public funding, it harms patients and leaves gaps in medical evidence. This makes it very difficult to determine how safe and effective treatments actually are.

Nordic countries have recently changed regulations that require institutions to make the results of drug and device trials public on registries within 12 months of completion. While clinical trials which ended in the years prior to 2023 are not included in this legislation, both the Declaration of Helsinki and World Health Organization have clearly stated for years that the timely public sharing of results is an ethical obligation.

Matteo Bruschettini, Director of Cochrane Sweden, who co-authored the report, said:  “At Cochrane we highly value that findings of all studies become available. Otherwise, the synthesis of the evidence misses information thus resulting in misleading conclusions. This ultimately impacts the patients, clinicians and policy makers who need to make decisions based on a distorted picture of the evidence. This report should encourage initiatives to deal with this issue of medical research waste in the Nordic countries.”

The report calls for policy makers in Denmark, Iceland, Finland, Norway and Sweden to adopt national legislation requiring that the results of all clinical trials are made public and to set up monitoring mechanisms. It also calls for national medicines regulators and research funders to put in structures to prevent research waste and ensure that clinical trial results are made public. This is in line with WHO recommendations which urged ethics committees, regulatory authorities, professional bodies, sponsors, investigators, and funding agencies to act in their jurisdictions to ensure results from all clinical trials are reported and publicly disclosed.

The report has already received attention in Swedish media.

Cochrane will continue to advocate for improved clinical trial transparency, and will monitor progress in these countries with interest.

Thursday, February 8, 2024
Harry Dayantis

Cochrane seeks Geographic Groups/Program Manager

8 months ago

Specifications: Permanent – Full Time
Salary:  £42,000 per Annum  
Location: (Remote – Flexible) UK, Germany, Denmark. Candidates anywhere from the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: CEOO
Closing date: 18 February 2024
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

As a Manager within Cochrane’s Central Executive Team, you will support Cochrane’s Geographic Groups, Networks, and Fields, play a pivotal role in supporting sustainable development, coordinating activities, and enhancing accountability frameworks. This position focuses on fostering collaboration, overseeing communication, and promoting growth within Cochrane’s global networks.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

  • An opportunity to truly impact health globally.  
  • A flexible work environment  
  • A comprehensive onboarding experiences.
  • An environment where people feel welcome, heard, and included, regardless of their differences.

Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  • For further information on the role and how to apply,
  • The deadline to receive your application is 18th Feb, 2024.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
  • Read our Recruitment Privacy Statement
Friday, February 2, 2024 Category: Jobs
Lydia Parsonson

Cochrane at the WHO Executive Board 2024

8 months ago

Last week, Cochrane participated in the 154th session of the World Health Organization (WHO) Executive Board meeting in Geneva.

The Executive Board is composed of 34 technically qualified representatives from different Member States, elected for three-year terms. Every January, the Executive Board meets at WHO headquarters to discuss global public health priorities for the year ahead and set the agenda for the World Health Assembly.

In addition to the Executive Board, all Member States and civil society organizations in official relations with WHO, such as Cochrane, are given the opportunity to contribute. This provided our delegation a great platform to advocate for evidence-based health policy. 

The session began with an opening statement by WHO Director-General. He highlighted the key achievements of the previous year, including the landmark decision to include life-changing treatments for multiple sclerosis drugs in the Essential Medicines List, which Cochrane Multiple Sclerosis and Rare Diseases of the CNS played a key role in.

WHO’s 14th General Programme of Work (GPW14) was a major focus of this year’s meeting. GPW14 is a medium-term strategy agreed by Member States and will defines the direction of WHO’s work (including on evidence-based health) for 2025-28, with the goal to promote, provide, and protect health. 

Emma Thompson, Cochrane’s Advocacy and Partnerships Lead, made a statement in front of Member States and WHO’s Director-General, speaking on behalf of Cochrane in applauding the draft GPW’s recognition of WHO’s science and evidence-based leadership, particularly highlighting the importance of high-quality evidence in health decision making. 

In addition to the official planned activities at the Executive Board meeting, Cochrane’s delegation used the opportunity to meet with several different WHO departments to discuss plans for Cochrane’s Scientific Strategy, which is currently in development, and opportunities for our next joint workplan.

Our delegation had many productive conversations with key individuals and teams on how Cochrane and WHO can continue to work together to address global public health priorities in the coming years. Supported by our years of relationship building, collaboration and advocacy, we held meetings with many WHO teams, covering a wide range of portfolios including maternal, newborn and child health; essential medicines; malaria, tropical diseases; nutrition; clinical trials; guidelines; health emergencies; and science. 

Another key highlight of the week was a meeting between Cochrane’s Editor-in-Chief, Dr Karla Soares-Weiser, and the Director of the Pan American Health Organization (PAHO), Dr Jarbas Barbosa and Dr Rhonda Sealey-Thomas, PAHO Assistant Director. During the meeting, they discussed collaboration between Cochrane and PAHO, which is underpinned by a new memorandum of understanding and Dr Soares-Weiser highlighted Cochrane’s enthusiasm for the formalisation of this partnership.

Thursday, February 1, 2024 Category: The difference we make
Muriah Umoquit

Early bird registration now open for the Global Evidence Summit

8 months ago

Today marks the official opening of registration for attendance at the second Global Evidence Summit (GES) 2024. Organized by the world’s leading organizations in evidence synthesis and evidence-based practice, including Cochrane, JBI, Guidelines International Network (GIN), and The Campbell Collaboration, the summit is set to take place in the historical city of Prague, Czech Republic, from 10 to 13 September 2024, with satellite meetings on 9 September 2024.

The GES is intended as a multi-disciplinary and cross-cultural event to exchange ideas about how we best produce, summarise and disseminate evidence to inform policy and practice, and using that evidence to improve people’s lives across the world. The summit will feature plenary keynote speakers, special sessions with panel experts, and traditional conference elements like posters and oral presentations. There will also be a robust social program to make sure there are plenty of opportunities to network and have conversations across sectors, such as health, education, social justice, the environment, and climate change. The programme domains include:

  • Sustainable development agenda
  • Research integrity & making evidence accessible
  • Power of synergy in evidence & synthesis products
  • Evidence translation & implementation
  • Advocating for greater evidence communication & use of evidence
  • From global evidence to local impact 

Miloslav Klugar, Chair of the Scientific and Local Organising Committee, extends a warm welcome:

“On behalf of our organising partners, I invite you all to join us for the eagerly anticipated 2nd Global Evidence Summit. You belong at GES! It’s a unique gathering of research and scientists, policymakers and managers but also students, consumers and activities, and patients and caregivers. This is a unique opportunity for people across the globe to get involved in evidence-based practice, with a shared mission to provide a platform to discuss critical issues across different sectors, including health, education, social justice, the environment and climate change.”  

Catherine Spencer, Cochrane's CEO, emphasizing the significance of the GES in fostering synergies and knowledge sharing within the global evidence community:

" I encourage the Cochrane Community to take advantage of Early Bird Registration for the 2nd Global Evidence Summit. Your participation will not only enrich your knowledge but also contribute to a global movement towards impactful, evidence-informed decision-making. Let's unite for #GES2024 and contribute to advancing evidence-based practice globally! We look forward to seeing you there!"

 

Early-bird registration is now open until 13 June. Standard registration is open until 14 August with late/onsite registration available. We also offer discounts to those from low-income economies as well as patients/consumers and students.

Thursday, February 29, 2024
Muriah Umoquit

Cochrane seeks Consumer Support Officer - remote, flexible

8 months 1 week ago

Specifications: Fixed term (2 years), 0.6 FTE
Salary:  £35,000 pro-rata
Location: (Remote – Flexible) Candidates anywhere from the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Closing date:  6 February 2024 

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Consumer Support Officer will work closely with Cochrane’s Consumer Engagement Officer to support the involvement of consumers (patients, carers and the public) in the Wellcome-funded GALENOS project, including in systematic reviews about mental health topics. Support of consumers in this work will involve connecting consumers with lived experience of mental health challenges to researchers, developing learning resources to support consumer involvement in systematic reviews, and generally promoting patient and public involvement in the systematic review space.  

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

  • An opportunity to truly impact health globally.  
  • A flexible work environment  
  • A comprehensive onboarding experiences.
  • An environment where people feel welcome, heard, and included, regardless of their differences.

Cochrane welcomes applications from a wide range of perspectives, experiences, locations, and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

  • For further information on the role and how to apply
  • The deadline to receive your application is 6th Feb, 2024.
  • The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
  • Read our Recruitment Privacy Statement
Wednesday, January 24, 2024 Category: Jobs
Lydia Parsonson
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9 hours 36 minutes ago
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