The ROBINS-I tool is a risk of bias tool to assess non-randomized studies of interventions. The relevant chapter in the Cochrane Handbook for Systematic Reviews of Interventions Chapter 25, titled ‘Assessing risk of bias in a non-randomized study’. Up-to-date information from the developers on ROBINS-I is available via the Risk of Bias tools website: https://www.riskofbias.info/
Cochrane Scientific Committee recommendation (Full statement, July 2017):
ROBINS-I is the preferred tool to be used in Cochrane Reviews for non-randomized studies of interventions, although it is not mandatory, and will require author teams to have sufficient knowledge and experience to apply the tool. An alternative option is the Newcastle-Ottawa Scale. Please await further announcements on guidance and support to implement this tool.
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