Rare events are a common problem in Cochrane reviews, especially for secondary and safety outcomes. In the presence of rare events, standard meta-analytical models have important limitations and may lead to biased results. The objective of this web clinic was to provide guidance on handling rare events in a Cochrane review, present the properties of the inverse variance method and explain why this method is problematic when outcome data are rare.

Posted by Ingrid Arevalo-Rodriguez (Methods Implementation Editor)

The Risk of Bias In Non-randomised Studies – of Interventions (ROBINS-I) tool allows authors to evaluate the risk of bias in the results of non-randomised studies that compare the effects of interventions (NRSI). The ROBINS-I tool was originally developed by members of the Cochrane Bias Methods Group and the Cochrane Non-Randomised Studies Methods Group.

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Statistics Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Screening and Diagnostics Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Rapid Reviews Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Qualitative and Implementation Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Prospective Meta-Analysis Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Prognosis Methods Group in the spotlight. 

We are celebrating the achievements of Cochrane’s Methods Groups from the last year. Today we are putting Priority Setting Methods Group in the spotlight.